The non-silicone formula delivers actives deep within the dermal layer of skin to interrupt repetitive muscle contractions that have been shown to result in wrinkle formation. See how rare silicone-free products are in our "Just the Facts" tab product comparisons. How much more effective is a product formulated to work in the dermal layers of the skin when silicones are not present? This is the first product to tap into the magic of Acetyl hexapeptide-3 (AH-3) without using silicones, fillers, excess preservatives, or artificial color or fragrance. NaturdermxTM is a scent-free, hydrophilic balanced, anti-aging pH balanced, antioxidant powerhouse! .

Rather than using multiple ingredients known to produce good effects, NaturDerm™ searches for the most effective ingredients to deliver specific amplified results. Why spend money on peptides that work before the muscle contraction, or after the muscle contraction - when the whole point is to stop the muscle contraction?

Synthetic amino acid peptides that mimic several of the compounds necessary to conduct neurotransmitter release, and the resulting muscle contraction, have revolutionized the skin care industry. This conduction requires a complex of 3 compounds that create a “zip-lock” connection between the neurons for the contraction to occur. Block the “zip-lock”, and you stop the contraction - it is that simple. You would never know it is simple by the misinformation that exists in the marketing of these products. Please see our store pages for a breakdown of the physiology and terms. AH-3 mimics one of those compounds. Science's gift to aging skin, AH-3 has been shown after 15 days to decrease the depth of eye wrinkles by 17%, after 30 days a whopping 27%!

Europeans between the ages of 15-30 spent as much on anti-aging products as men in the US, 11 billion USD. These young women understand the science of anti-aging. They believe if they use products that inhibit repetitive facial contractions it will have an impact on what they see in the mirror in 10-20-30 years to come.

Naturdermx™ ultimate peptide complex also contains organic Grape Seed Extract, which contains high levels of ECGC and Resveratrol.
Robert Schwartz, MD, MPH, Professor and Head of Dermatology, Professor of Medicine, Professor of Pediatrics, Professor of Pathology, and Professor of Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School said the following in his article titled, "Cosmeceuticals" (web MD). The following are quotes from the article Dr. Schwartz co-authored with Santiago Centurion, MD and Cristina Solis, RN. Dr. Schwartz states, " Cosmeceuticals represent a marriage between cosmetics and pharmaceuticals. Like cosmetics, cosmeceuticals are topically applied, but they contain ingredients that influence the biological function of the skin.""Resveratrol and polydatins are glucopyransosides found in many fruits and vegetables, the highest concentrations being found in grape skins, which synthesize these compounds in response to exposure to UV-A and UV-B and fungal pathogens. Biologic activities of these glucopyranosides include potent free radical scavenging activity, with cardioprotection and neuroprotection and inhibition of lipid peroxidation simiar to that seen with vitamins C and E." "Polyphenolic compounds (eg, catechins, flavonols, thioflavins, thearubigins), also know as epicatechins, are antioxidant in nature. These compounds, tested against human keratinocyte cells stressed by UV-B irradiation, showed high antioxidative properties." "One of the major and most chemopreventive consituents responsible for the biochemical or pharmacologic effects is -epigallocatechin-3-gallate (EGCG), found in green tea."